A multiple gadolinium complex decorated fullerene as a highly sensitive T(1) contrast agent.

نویسندگان

  • Lirong Wang
  • Xianglong Zhu
  • Xingyan Tang
  • Changqiang Wu
  • Zijian Zhou
  • Chengjie Sun
  • Shun-Liu Deng
  • Hua Ai
  • Jinhao Gao
چکیده

We report a simple strategy to construct a multiple gadolinium complex decorated fullerene (CGDn) as an enhanced T1 contrast agent. The CGDn exhibits much higher T1 relaxivity (∼49.7 mM(-1) s(-1)) than individual Gd-DOTA, and shows excellent T1 contrast enhancement ability both in vitro and in vivo.

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عنوان ژورنال:
  • Chemical communications

دوره 51 21  شماره 

صفحات  -

تاریخ انتشار 2015